Showing posts with label monoclonal antibodies. Show all posts
Showing posts with label monoclonal antibodies. Show all posts

Tuesday, September 5, 2023

Alpha Lifetech Inc. offers rabbit monoclonal antibodies

 In the realm of biotechnology and scientific research, obtaining high-quality antibodies is essential for accurate and reliable results. Alpha Lifetech Inc. has developed a groundbreaking monoclonal antibody technology specifically tailored for rabbit monoclonal antibody production.

Rabbit monoclonal antibodies have gained significant attention in recent years due to their unique characteristics and advantages over traditional mouse monoclonal antibodies.

 

The Key Benefits of Rabbit Monoclonal Antibodies:

 

Enhanced Sensitivity and Specificity: Rabbit monoclonal antibodies are known for their high specificity and sensitivity, enabling them to recognize and bind their target antigens with greater precision. This makes them particularly valuable in various applications, such as diagnostic tests and research purposes. 

Broadened Epitope Recognition: Rabbit immune systems generate a broader and more diverse range of antibodies compared to mice. This diversity allows rabbit monoclonal antibodies to recognize a wider variety of antigenic epitopes, including those that may be poorly immunogenic in mice.

Improved Stability and Affinity: Rabbit monoclonal antibodies typically exhibit better stability and affinity towards their target antigens than mouse-derived antibodies. This improved affinity and stability can lead to enhanced performance in various applications, including immunoassays, flow cytometry, and immunohistochemistry.

Faster Development and Production: Alpha Lifetech Inc.'s cutting-edge technology streamlines the process of rabbit monoclonal antibody production, enabling researchers to obtain high-quality monoclonal antibodies more quickly and efficiently.

At Alpha Lifetech Inc., we pride ourselves on offering top-quality rabbit monoclonal antibodies tailored to meet the specific needs of our clients. Alpha Lifetech Inc. can offer thousands of rabbit monoclonal antibodies against various biomolecules to satisfy your requirements, based on cell fusion technology, phage display technologyand single B cell screening technology. Our expert team of scientists utilizes cutting-edge technologies and advanced techniques to generate highly specific and high-affinity rabbit monoclonal antibodies. We offer a comprehensive catalog of antibodies for various targets and research applications and customized services to develop and optimize antibodies according to your unique requirements.

Whether you're investigating novel targets, developing diagnostic assays, or studying complex biological processes, Alpha Lifetech Inc. is your trusted partner for exceptional rabbit monoclonal antibodies! For more information, please contact us and our technical support team will get back to you as soon as possible.

Thursday, August 31, 2023

Monoclonal Antibodies

    Monoclonal antibodies (mAbs) are immunoglobulins designed to target a specific epitope on an antigen. The antigen-binding region of the mAb is formed by the variable domains of the heavy and light chains and contains the complementarity-determining region that imparts high specificity for the target antigen. The monoclonal antibodies (mAb or moAb) recognize only one epitope per antigen and are less likely than polyclonal antibodies to react against other proteins. Monoclonal antibodies can be used to identify specific antigens. Due to their essential functions in various areas, monoclonal antibodies have become popular molecules.

    The first monoclonal antibody was generated in mice in 1975 by Milstein and Kohler using the hybridoma technique.

    The most popular approach for creating monoclonal antibodies is still hybridoma production. The hybridomas that produce monoclonal antibodies from the stable fusions to develop in vitro are chosen, sub-cloned, and formed. These clones are then cultivated, and either the cells themselves or the lysates from the cell culture are used to purify the antibodies they make. Each monoclonal antibody's specificity is determined by its binding site on the target protein.


Monoclonal antibodies (mAbs) production (Polyclonal and Monoclonal Antibody Production | Microbiology | | Course Hero)

    Alternative techniques for creating monoclonal antibodies have become available. The so-called "phage-display method" allowed for the specificity screening of recombinant antigen-binding antibodies from a library of fusions to a carrier phage protein. The constant region of recombinant antibodies may now be tailored due to significant advancements in their manufacture, leading to cell lines that can produce them. The benefit of this novel manufacturing approach is that it avoids the problems associated with a hybridoma's long-term stability, including the eventual loss of a priceless clone.


Advantages of Monoclonal Antibodies

(1) Batch to batch reproducibility

(2) The possibility of producing large amounts of identical antibodies

(3) Highly specific to a unique epitope

(4) Low cross-reactivity

(5) Most sensitive in tests where protein levels need to be quantified

 

Alpha Lifetech Inc. provides highly validated monoclonal antibodies to support your research. We offer thousands of mouse monoclonal antibodies, rabbit monoclonal antibodies, and over 700 high-quality recombinantly expressed biosimilar antibodies. The antibodies undergo comprehensive validation testing to ensure high quality, high consistency, and specific binding to the molecule targeted and approved for your research use. Based on our professional antibody R&D team and rich experience in antibody production, we are confident in the quality of our antibody products and strive to accelerate your research. The mature technical route and dependable quality will save you time.

    Whether you are ordering our antibodies for your research use or talking to one of our technical service representatives, our staff is dedicated to providing professional support. Please feel free to contact us for more information about our products and related promotions.

Stable Cell Line Construction Service

     Alpha Lifetech Inc.  is experienced in cell line construction. We are committed to providing high-quality stable cell line construction...